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  • Tislelizumab plus chemotherapy versus placebo plus . . .
    The options for first-line treatment of advanced oesophageal squamous cell carcinoma are scarce, and the outcomes remain poor The anti-PD-1 antibody, tislelizumab, has shown antitumour activity in previously treated patients with advanced oesophageal squamous cell carcinoma We report interim analysis results from the RATIONALE-306 study, which aimed to assess tislelizumab plus chemotherapy
  • Tislelizumab Combined With Induction Chemotherapy and . . .
    To evaluate the efficacy and safety of adding tislelizumab to induction chemotherapy and concurrent chemoradiotherapy (CRT), with or without maintenance immunotherapy, in patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC)
  • Tislelizumab Versus Chemotherapy as Second-Line Treatment for . . .
    PURPOSEPatients with advanced or metastatic esophageal squamous cell carcinoma (ESCC) have poor prognosis For these patients, treatment options are limited after first-line systemic therapy PATIENTS AND METHODSIn this open-label phase III clinical study,
  • ESCC and GC GEJC Treatment | TEVIMBRA® (tislelizumab-jsgr)
    TEVIMBRA is a prescription medicine used to treat adults with: cancer of the tube that connects your throat to your stomach (esophageal cancer) TEVIMBRA may be used in combination with chemotherapy that contains platinum as your first treatment when your esophageal cancer: is a type called squamous cell carcinoma, and cannot be removed with surgery or has spread to other parts of the body
  • TEVIMBRA - accessdata. fda. gov
    1 INDICATIONS AND USAGE 1 1 Esophageal Cancer First-Line Treatment of Esophageal Squamous Cell Carcinoma TEVIMBRA, in combination with platinum-containing chemotherapy, is indicated for the first-line treatment of adults with unresectable or metastatic esophageal squamous cell carcinoma (ESCC) whose tumors express PD-L1 (≥1)
  • Oncology Drug Reference Sheet: Tislelizumab-Jsgr - ons. org
    Tislelizumab-jsgr (Tevimbra®) is a programmed cell death protein-1 (PD-1) blocking antibody approved in the United States in 2024 for the treatment of certain esophageal and gastric cancers It is administered via IV and works by enhancing the immune system’s ability to target cancer cells
  • Frontiers | Tislelizumab efficacy and safety compared to . . .
    Tislelizumab efficacy and safety compared to other anti–PD-1s: a network meta-analysis of first-line therapies for unresectable, locally advanced or metastatic esophageal squamous cell carcinoma
  • Tislelizumab: Side Effects, Uses, Dosage, Interactions, Warnings
    Tislelizumab is a prescription medication indicated for unresectable or metastatic esophageal squamous cell carcinoma (ESCC) in patients previously treated with systemic chemotherapy that did not include a PD-(L) 1 inhibitor
  • First-Line Tislelizumab Plus Chemotherapy Approved in ESCC . . .
    The FDA today approved tislelizumab (Tevimbra; BeiGene) plus chemotherapy for the first-line treatment of patients with unresectable or metastatic esophageal squamous cell carcinoma (ESCC) whose
  • PET CT-Guided Neoadjuvant Tislelizumab plus Chemotherapy . . .
    Subsequently, all patients received three cycles of tislelizumab 200 mg intravenously In addition, PET responders received chemotherapy and PET nonresponders received chemoradiotherapy as neoadjuvant treatment followed by surgery The primary endpoint was the pathologic complete response (pCR) rate





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